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Sebastian Wachsmann Hogiu

Academic title(s): 

Professor

Undergraduate Program Director

Sebastian Wachsmann Hogiu
Contact Information
Email address: 
sebastian.wachsmannhogiu [at] mcgill.ca
Phone: 
514.398.1520
Office: 
McConnell聽Engineering Building, Room 362
Degree(s): 

BSc: Bucharest University, Physics, Biophysics

PhD: Humboldt University, Berlin, Experimental Physics,

PostDoc: Carnegie Mellon University, Pittsburgh, Chemical Physics

Previous Appointments: Carnegie Mellon University, Pittsburgh; Cedars Sinai Medical Center, Los Angeles; University of California Davis, Davis; Intellectual Ventures / Global Good, Seattle

Areas of interest: 
  • Biosensors
  • Biomimetics
  • Point of need and wearable technologies
  • Quantum Biology
Courses: 
  • BIEN 210: Electrical and Optical Properties of Optical Systems
  • BIEN 390: Bioengineering Laboratory
  • BIEN 560: Design of Biosensors
Selected publications: 
  1. Adam Melnyk, Lena Kozarov, Sebastian Wachsmann-Hogiu, 鈥� A deconvolution approach to modelling surges in COVID-19 cases and deaths鈥�, Scientific Reports, 13 (1), 2361.
  2. Meruyert Imanbekova, Ayse Mine Saridag, Mehmet Kahraman, Juanjuan Liu, Humeyra Caglayan, and Sebastian Wachsmann-Hogiu, 鈥淐omplementary Metal Oxide Semiconductor Based Sensing Platform for Trapping, Imaging, and Chemical Characterization of Biological Samples鈥�. ACS Applied Optical Materials, 2022, .
  3. Juanjuan Liu, Sebastian Wachsmann-Hogiu, 鈥淧rogress and Challenges of Point of Need Photonic Biosensors for the Diagnosis of COVIDS-19 Infections and Immunity鈥�, Biosensors, 2022,
  4. Meruyert Imanbekova, Sorina Suarasan, Yao Lu, Sarah Jurchuk, Sebastian Wachsmann-Hogiu, 鈥淩ecent advances in label-free characterization of extracellular vesicles鈥�, Nanophotonics, 04/2022.
  5. Reza Abbasi, Juanjuan Liu, Sorina Suarasan, Sebastian Wachsmann-Hogiu, 鈥淪E-ECL on a CMOS: a miniaturized electrochemiluminescence system鈥�, Lab on a Chip, 02/2022.
  6. Juanjuan Liu, Roozbeh Siavash Moakhar, Sara Mahshid, Fartash Vasefi, Sebastian Wachsmann-Hogiu, 鈥淢ultimodal electrochemical and SERS platform for chlorphenapyr detection鈥�, Applied Surface Science, 2021, Vol 566, pp. 150617.
  7. Meruyert Imanbekova, Sorina Suarasan, Tatu Rojalin, Rachel Mizenko, Silvia Hilt, Meghna Mathur, Paula Lepine, Michael Nicouleau, Nguyen-Vi Mohamed, Thomas Durcan, Randy Carney, John Voss, Sebastian Wachsmann-Hogiu, 鈥淚dentification of amyloid beta in small extracellular vesicles via Raman spectroscopy鈥�, Nanoscale Advances, 2021, 3, 4119-4132.
  8. Juanjuan Liu, Mahsa Jalali, Sara Mahshid, Sebastian Wachsmann-Hogiu, "Are plasmonic optical biosensors ready for use in point-of-need applications?", Analyst, 2020, Vol. 145, pp. 364-384.
  9. Sorina Suarasan, Juanjuan Liu, Meruyert Imanbekova, Tatu Rojalin, Silvia Hilt, John C Voss, Sebastian Wachsmann-Hogiu, "Superhydrophobic bowl-like SERS substrates patterned from CMOS sensors for extracellular vesicle characterization", Journal of Materials Chemistry B, 2020, Vol. 8, pp. 8845-8852.
  10. Juanjuan Liu, Roozbeh Siavash Moakhar, Ayyappasamy Sudalaiyadum Perumal, Horia Nicolae Roman, Sara Mahshid, Sebastian Wachsmann-Hogiu, "A AgNP-deposited commercial electrochemistry test strip as a platform for urea detection", Scientific Reports, 2020, Vol 10, pp. 1-11.
  11. Meruyert Imanbekova, Ayyappasamy Sudalaiyadum Perumal, Sara Kheireddine, Dan V Nicolau, Sebastian Wachsmann-Hogiu, 鈥淟ensless, reflection-based dark-field microscopy (RDFM) on a CMOS chip", Biomedical Optics Express, 2020, Vol. 11, pp. 4942-4959.
  12. Sebastian Wachsmann-Hogiu, Zachary J Smith, Mehmet Kahraman, 鈥溾��, Frontiers in Chemistry, 2019, 7, pp.865
  13. Sara Kheireddine, Zachary J Smith, Dan V Nicolau, Sebastian Wachsmann-Hogiu, 鈥溾��, Biomedical optics express, 2019, 10(9), pp. 4369-4380.
  14. Sara Kheireddine, Ayyappasamy Sudalaiyadum Perumal, Zachary J. Smith, Dan V. Nicolau, and Sebastian Wachsmann-Hogiu, Dual-Phone Illumination-Imaging System for High Resolution and Large Field of View Multi-Modal Microscopy, Lab on a Chip, 2019.
  15. Korkmaz, M. Kenton, G. Aksin, M. Kahraman, S. Wachsmann-Hogiu, 鈥淚nexpensive and flexible substrates on adhesive tape based on biosilica plasmonic nanocomposites鈥�, ACS Applied Nano Materials, 2018/8/17.
  16. Rebeca Ferraz de Menezes, Catherine Malinda Harvey, Marleny Elizabeth M谩rquez de Mart铆nez Gerbi, Zachary J Smith, Dan Smith, Juan C Ivaldi, Alton Phillips, James W Chan, Sebastian Wachsmann-Hogiu, 鈥淔s-laser ablation of teeth is temperature limited and provides information about the ablated components鈥� Journal of Biophotonics 05/2017;, DOI:10.1002/jbio.201700042
  17. Mehmet Kahraman, Emma R. Mullen, Aysun Korkmaz, Sebastian Wachsmann-Hogiu, 鈥淔undamentals and applications of SERS-based bioanalytical sensing鈥�, Nanophotonics 01/2017; 6(5)., DOI:10.1515/nanoph-2016-0174.
  18. Ruby K. Gill, Zachary J. Smith, Changwon Lee, and Sebastian Wachsmann-Hogiu, 鈥�The effects of laser repetition rate on femtosecond laser ablation of dry bone: a thermal and LIBS study鈥�, Journal of Biophotonics, 9 (1-2), 171-180, 2016.
  19. Tingjuan Gao, Zachary Smith, Tzu-yin Lin, Danielle Carrade Holt, Stephen M Lane, Dennis L Matthews, Denis M Dwyre, James Hood, Sebastian Wachsmann-Hogiu, 鈥濃��, Analytical chemistry 87 (23), 11854-11862, 2015.
  20. Ruby K Gill, Zachary J Smith, Ripul R Panchal, John W Bishop, Regina Gandour-Edwards, Sebastian Wachsmann-Hogiu, , Biomedical Optics Express, 6 (12), 4850-4858, 2015.
  21. Kaiqin Chu, Zachary J. Smith, Sebastian Wachsmann-Hogiu, 鈥淒eveloping an inexpensive blood imaging system: where are we now?鈥�, Expert Review of Medical Devices. 12(5), 613-627, 2015.
  22. Changwon Lee, Randy P. Carney, Sidhartha Hazari, Zachary Smith, Alisha Knudson, Christopher S. Robertson, Kit S. Lam and Sebastian Wachsmann-Hogiu*, 鈥�3D plasmonic nanobowl platform for the study of exosomes in solution鈥�, Nanoscale, 2015, DOI: 10.1039/C5NR01333J.
  23. Zachary J Smith, Changwon Lee, Tatu Rojalin, Randy P Carney, Sidhartha Hazari, Alisha Knudson, Kit Lam, Heikki Saari, Elisa Lazaro Iba帽ez, Tapani Viitala, Timo Laaksonen, Marjo Yliperttula, Sebastian Wachsmann-Hogiu, , Journal of Extracellular Vesicles, 5, 2015
  24. Changwon Lee, Christopher S. Robertson, An H. Nguyen, Mehmet Kahraman, Sebastian Wachsmann-Hogiu, 鈥�Thickness of a metallic film, in addition to its roughness, plays a significant role in SERS activity鈥�, online, Scientific Reports 5, 2015
  25. Ralph Green, Sebastian Wachsmann-Hogiu, 鈥淒evelopment, history, and future of automated cell counters鈥�, Clinics in Laboratory Medicine, 35, 2015, pp. 1-10.
  26. Mehmet Kahraman, Sebastian Wachsmann-Hogiu, 鈥淟abel-Free and Direct Protein Detection on 3D Plasmonic Nanovoid Structures using Surface-Enhanced Raman Scattering鈥�, Analytica Chimica Acta, 856, 2015, pp. 74-81.
  27. R. K. Gill, F. Knorr, Z. J. Smith, M. Kahraman, D. Madsen, D. S. Larsen, S. Wachsmann-Hogiu, 鈥淐haracterization of Femtosecond Laser Induced Breakdown Spectroscopy (fsLIBS) and Applications for Biological Samples鈥�, Applied Spectroscopy, Vol. 68, 9, 2014, pp. 949-54
  28. Z. J. Smith, T. Gao, K. Chu, S. M. Lane, D. L. Matthews, D. M. Dwyre, J. Hood, K. Tatsukawa, L. Heifetz, and S. Wachsmann-Hogiu, 鈥淪ingle-step preparation and image-based counting of minute volumes of human blood鈥�, Lab on a Chip, 14 (16), 2014, pp. 3029-3036.
  29. M. A. S. de Oliveira, Z. J. Smith, F. Knorr, R. E. de Araujo, and S.Wachsmann-Hogiu, 鈥淟ong Term Raman Spectral Study of Power-Dependent Photodamage in Red Blood Cells鈥�, Applied Physics Letters, 104, 2014, 103702.
  30. M. Kahraman, P. Daggumati, O. Kurtulus, E. Seker, S. Wachsmann-Hogiu, 鈥淔abrication and Characterization of Flexible and Tunable Plasmonic Nanostructures鈥�, Scientific Reports 3, 2013: 3396 | DOI: 10.1038/srep03396.
  31. T. Zhang, S. Osborn, C. Brandow, D. Dwyre, R. Green, S.M. Lane, S. Wachsmann-Hogiu, 鈥�Structured Illumination-Based Super-Resolution Optical Microscopy for Hemato- and Cyto-Pathology Applications鈥�, Analytical Cellular Pathology, 36 (1) 2013, pp. 27-35.
  32. M. Kahraman , B.N. Balz and S. Wachsmann-Hogiu, 鈥淗ydrophobicity-driven self-assembly of protein and silver nanoparticles for protein detection using surface-enhanced Raman scattering鈥�, Analyst, 138 (10), 2013, pp. 2906-2913.
  33. Z. J. Smith, T. R. Huser, S. Wachsmann-Hogiu, 鈥淩aman scattering in pathology鈥�, Analytical Cellular Pathology, 2012, 35 (3), pp. 145-163.
  34. Z. J. Smith, C.-W. Chang, L. S. Lawson, S. M. Lane, S. Wachsmann-Hogiu, 鈥淧recise Monitoring of Chemical Changes through Localization Analysis of Dynamic Spectra (LADS),鈥� Applied Spectroscopy, 67(2), 2013, pp. 187-195.
  35. Z. J. Smith*, K.Q Chu, S. Wachsmann-Hogiu, 鈥淣anometer-Scale Sizing Accuracy of Particle Suspensions on an Unmodified Cell Phone Using Elastic Light Scattering鈥�, PLoSONE, Oct. 2nd 2012, 7(10), e46030.
  36. Z. J. Smith, S. Strombom, S. Wachsmann-Hogiu, 鈥淢ultivariate optical computing using a digital micromirror device for fluorescence and Raman spectroscopy鈥�, Optics Express, 2011, Vol. 19, Issue 18, pp. 16950-16962.
  37. Z. J. Smith, K. Chu, A. R. Espenson, M. Rahimzadeh, A. Gryshuk, M. Molinaro, D. M. Dwyre, S. M. Lane, D. Matthews, S. Wachsmann-Hogiu, 鈥淐ell-phone-based platform for biomedical device development and education applications鈥�, PLoSONE, 2011, 6(3): e17150.
  38. C. V. Pagba, S. M. Lane, S. Wachsmann-Hogiu, 鈥淐onformational changes in quadrulpex oligonucleotide structures probed by Raman spectroscopy鈥�, Biomedical Optics Express, Vol. 2, Issue 2, 2011, pp. 207-217.
  39. F. Knorr, Z. J. Smith, S. Wachsmann-Hogiu, 鈥淒evelopment of a time-gated system for Raman spectroscopy of biological samples鈥�, Optics Express, Vol. 18, No. 19, 2010, pp. 20049-20058.
  40. C. V. Pagba, S. M. Lane, H. Cho, S. Wachsmann-Hogiu, 鈥淒irect detection of aptamer-thrombin binding via surface-enhanced Raman spectroscopy鈥�, J. Biomed. Opt., Vol. 15 (4), 2010, 047006.
  41. C. V. Pagba, S. M. Lane, S. Wachsmann-Hogiu, 鈥淩aman and SERS studies of the 15-mer DNA Thrombin Binding Aptamer鈥�, Journal of Raman Spectroscopy, Vol. 41, Issue 3, 2010, pp. 241-247.
  42. S. Wachsmann-Hogiu, T. Weeks, T. Huser, 鈥淐hemical analysis in vivo and in vitro Raman spectroscopy 鈥� from single cells to humans鈥�, Curr. Opinions in Biotech., Vol. 20, 2009, pp. 63-73
  43. S. Wachsmann-Hogiu, L. A. Peteanu, L. A. Liu, D. J. Yaron, J. Wildeman, 鈥淭he Effects of Structural and Micro- Environmental Disorder on the Electronic Properties of MEH-PPV and Related Oligomers鈥�, J. Phys. Chem. B, vol. 107, 2003, pp. 5133-5143.
  44. S. Wachsmann-Hogiu, W. Werncke, J. Dreyer, A. I. Vodchits, K.-W. Brzezinka, 鈥淯ltrafast intramolecular electron transfer studied by stationary vibrational and time-resolved resonance Raman spectroscopy combined with ab initio calculations鈥�, Recent Res. Devel. Chem. Physics, Vol. 2, 2001, pp. 83-106.
  45. S. Hogiu, J. Dreyer, M. Pfeiffer, K.-W. Brzezinka, W. Werncke, 鈥淰ibrational analysis and excited-state geometric changes of betaine-30 derived from Raman and infrared spectra combined with ab initio calculations鈥�, J. Raman Spectrosc., Vol. 31, Issue 8/9, 2000, pp. 797-803.
  46. S. Hogiu, W. Werncke, M. Pfeiffer, J. Dreyer, T. Elsaesser, 鈥淢ode-specific vibrational excitation and energy redistribution after ultrafast intramolecular electron transfer鈥�, J. Chem. Phys., Vol. 113, Issue 4, 2000, pp. 1587-1594.
  47. S. Hogiu, W. Werncke, M. Pfeiffer, T. Elsaesser, 鈥淢ode specific vibrational kinetics after intramolecular electron transfer studied by anti-Stokes Raman spectroscopy鈥�, Chem. Phys. Lett., Vol. 312, Issue 5-6, Oct. 1999, pp. 407-414.
  48. S. Hogiu, W. Werncke, M. Pfeiffer, A. Lau, 鈥淓vidence of strong vibronic coupling in the first excited singlet state of diphenylhexatriene by picosecond CARS spectroscopy鈥�, Chem. Phys. Lett., Vol. 303, Issue 1-2, 2 April 1999, pp. 218-222.
  49. S. Hogiu, W. Werncke, M. Pfeiffer, A. Lau, T. Steinke, 鈥淧icosecond time-resolved CARS spectroscopy of a mixed excited singlet state of diphenylhexatriene鈥�, Chem. Phys. Lett., Vol. 287, Issue 1-2, 24 April 1998, pp. 8-16.
  50. M.L. Pascu, B. Carstocea, G. Popescu, O. Gafencu, S. Apostol, N. Moise, M. Roman, S. Hogiu, 鈥淚maging corneal cells using low power beams鈥�, Lasers in Medical Science, Vol. 13, Issue 2, 1998, pp. 148-154.
  51. S. Hogiu, M. Enescu, M.L. Pascu, 鈥淒ynamic and thermodynamic effects of glycerol on bovine serum albumin in aqueous solution: a tryptophan phosphorescence study鈥�, J. of Photochem.Photobiol. B: Biology, Vol. 40, Issue 1, Aug. 1997, pp. 55-60.
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