Jacek Majewski
Associate Professor Human Genetics
E-mail: jacek.majewski [at] mcgill.ca
Research Area: Genomics & Bioinformatics; Computational Biology
Genomics and Epigenomics. The 3 billion nucleotides that make up our genome can be sequentially decoded to create a complex organism starting from a single cell. During differentiation, tissues acquire specific cell fates that are largely mediated by epigenetic modifications 鈥� DNA and chromatin changes. When disrupted, epigenetic defects result in abnormal development and cancer. We use high throughput genomics approaches, such as DNA, RNA, methylome, and ChIP-seq, to understand both normal and cancer processes. The focus of the lab is on computational analysis, but we actively collaborate with a number of laboratory scientists and clinicians.