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Honours Anatomy and Cell Biology (73 credits)

Offered by: Anatomy and Cell Biology     Degree: Bachelor of Science

Program Requirements

Students should register at the Major level in U1 and, if accepted, may enter the Honours program at the beginning of U2. To enter the program, the student must obtain a CGPA of at least 3.20 at the end of U1. For promotion to the U3 year of the Honours program, or for entry into the program at this level, the student must have a CGPA of at least 3.20 at the end of their U2 year. It is expected that at the beginning of the third year, the students who wish to continue in the Honours program will be those who feel that they are seriously interested in a career in Cell Biology. The Honours degree will be recommended after successful completion of the program with a CGPA of at least 3.20.

Required Courses (52 credits)

* Students who have taken the equivalent of CHEM 212, CHEM 222, and/or MATH 203 in CEGEP and receive a course exemption upon admission are exempt from the program requirement(s) and must replace these credits with elective course

  • ANAT 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2025

    Instructors: Vera Ugalde, Maria; Pause, Arnim; Reinhardt, Dieter; Fabian, Marc; Kiss, Robert; Kazak, Lawrence; Pastor, William; Cockburn, Katie (Winter)

  • ANAT 214 Systemic Human Anatomy (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Introduction to the gross anatomy of the various organ systems of head, neck and trunk regions of the human body. Emphasis on functional anatomy. Laboratory component includes exploration of the human body through cadaveric prosections, imaging and other materials.

    Terms: Fall 2024

    Instructors: Rolian, Campbell; Venne, Gabriel (Fall)

    • Fall

    • 2 hours lectures, 2 hours laboratory

    • Prerequisites: BIOL 112 (or CEGEP equivalent), PHGY 209 and PHGY 210

    • This course is limited in size, with guaranteed admission for all students enrolled in the Department of Anatomy and Cell Biology. Students in other programs will be permitted to enroll as space allows.

  • ANAT 261 Introduction to Dynamic Histology (4 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An introduction to light and electron microscopic anatomy in which cell and tissue dynamics will be explored in the principal tissues and organs of the body.

    Terms: Fall 2024

    Instructors: Mandato, Craig A.; Morales, Carlos R (Fall)

    • Fall

    • 3 hours lectures, 2 hours laboratory

    • Must be taken in U1 by students in Anatomy and Cell Biology programs

    • Prerequisite: BIOL 112 or CEGEP equivalent

    • Restriction: Open to students in biological sciences and others by special permission

  • ANAT 262 Introductory Molecular and Cell Biology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : The architectural, functional and temporal continuity of organelles and the cytoskeleton of mammalian cells is introduced as well as their functional integration in the phenomena of exocytosis, endocytosis, protein trafficking and cell motility and adhesion.

    Terms: Winter 2025

    Instructors: Presley, John; Stochaj, Ursula; Bechstedt, Susanne; Bui, Khanh Huy (Winter)

    • Winter

    • 3 hours lecture

    • Corequisites: ANAT 212 or BIOC 212 or BIOL 201

    • Restriction: Open to students in biological sciences and others by special permission

  • ANAT 432 Honours Research Project (9 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Supervised honours research project in biological sciences.

    Terms: Fall 2024, Winter 2025

    Instructors: Bui, Khanh Huy (Fall) Bui, Khanh Huy (Winter)

    • Prerequisite: BIOL 301

    • Restriction: For students in the Honours program.

    • Course opened to all Anatomy & Cell Biology students and other BSc students by special permission only.

  • BIOL 200 Molecular Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.

    Terms: Fall 2024

    Instructors: Champetier, Serge; Hastings, Kenneth E M; Lasko, Paul; Turney, Shaun; Reyes Lamothe, Rodrigo (Fall)

    • Fall

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 112 or equivalent

    • Corequisite: CHEM 212 or equivalent, or CHEM 204

  • BIOL 202 Basic Genetics (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.

    Terms: Winter 2025

    Instructors: Moon, Nam Sung; Nilson, Laura; Schoen, Daniel J; Hipfner, David; Champetier, Serge (Winter)

    • Winter

    • 3 hours lecture, 1 hour optional tutorial per week

    • Prerequisite: BIOL 200 or BIOL 219

    • Restriction: Not open to students who have taken or are taking LSCI 204 or BIOL 302.

  • BIOL 301 Cell and Molecular Laboratory (4 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : An introduction to biology research and communication with a focus on cell and molecular biology. Through conducting a series of project-based experiments and writing a final report, molecular and synthetic biology techniques such as gene cloning, manipulation, protein isolation and characterization and how research is conducted, analyzed and communicated will be addressed. In addition, an introduction to bioinformatics methods and their role in analysis will be provided.

    Terms: Fall 2024, Winter 2025

    Instructors: Hayer, Arnold; Harrison, Paul; Zheng, Huanquan; Leroux, Maxime (Fall) Zheng, Huanquan; Harrison, Paul; Leroux, Maxime; Hayer, Arnold (Winter)

    • Fall or Winter

    • 1 hour lecture and one 6-hour laboratory

    • Prerequisites: BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219

    • Restrictions: Not open to students who have taken or are taking BIOC 300, or BIOC 220 and BIOC 320. Requires departmental approval.

    • For approval email maxime.leroux [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.

  • CHEM 212 Introductory Organic Chemistry 1 (4 credits) *

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : A fundamental study of aliphatic compounds and saturated functional groups including modern concepts of bonding, reaction mechanisms, conformational analysis, spectroscopy, and stereochemistry.

    Terms: Fall 2024, Summer 2025

    Instructors: Vlaho, Danielle; Huot, Mitchell; Sirjoosingh, Pallavi; Tsantrizos, Youla S; Pavelka, Laura; Luedtke, Nathan (Fall) Sirjoosingh, Pallavi; Vlaho, Danielle; Huot, Mitchell (Summer)

    • Fall, Summer

    • Prerequisite: CHEM 110 and CHEM 120 or equivalent.

    • Restriction: Not open to students registered in Chemistry or Biochemistry. Not open to students who have taken or are taking CHEM 211, CHEM 242, or equivalent.

    • Each lab section is limited enrolment

    • Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().

  • CHEM 222 Introductory Organic Chemistry 2 (4 credits) *

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.

    Terms: Winter 2025, Summer 2025

    Instructors: Vlaho, Danielle; Huot, Mitchell; Sirjoosingh, Pallavi; Moitessier, Nicolas; Luedtke, Nathan (Winter) Vlaho, Danielle; Huot, Mitchell (Summer)

    • Winter, Summer

    • Prerequisite: CHEM 212 or CHEM 242 or equivalent.

    • Restriction: Not open to Chemistry or Biochemistry students. Not open to students who have taken or are taking CHEM 234 or CHEM252.

  • MIMM 214 Introductory Immunology: Elements of Immunity (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : Basic immunology, organs and cells, elements of innate immunity, phagocytes, complement, elements of adaptive immunity, B-cells, T-cells, antigen presenting cells, MHC genes and molecules, antigen processing and presentation, cytokines and chemokines. Emphasis on anatomy and the molecular and cellular players working together as a physiological system to maintain human health.

    Terms: Winter 2025

    Instructors: Chahal, Jasmin (Winter)

  • PHGY 209 Mammalian Physiology 1 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.

    Terms: Fall 2024

    Instructors: Vollrath, Melissa; Ragsdale, David S; Shrier, Alvin; Cook, Erik; Aguer, C茅line (Fall)

  • PHGY 210 Mammalian Physiology 2 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.

    Terms: Winter 2025

    Instructors: Vollrath, Melissa; Takano, Tomoko; Lauzon, Anne-Marie; White, John H; Aguer, C茅line (Winter)

3 credits from the following statistics courses:

  • BIOL 373 Biometry (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

    • Fall

    • 2 hours lecture and 2 hours laboratory

    • Prerequisite: MATH 112 or equivalent

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

  • MATH 203 Principles of Statistics 1 (3 credits) *

    Offered by: Mathematics and Statistics (Faculty of Science)

    Overview

    Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).

    Terms: Fall 2024, Winter 2025, Summer 2025

    Instructors: Stephens, David; Correa, Jose Andres (Fall) Sajjad, Alia (Winter)

    • No calculus prerequisites

    • Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.

  • PSYC 204 Introduction to Psychological Statistics (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.

    Terms: Fall 2024, Winter 2025

    Instructors: Kreitewolf, Jens (Fall) Kreitewolf, Jens (Winter)

    • Fall and Winter

    • Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300

    • This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

Complementary Courses (21 credits)

Complementary courses are selected as follows with a minimum of 6 credits at the 400 level or higher:

18 credits of advanced anatomy courses (AAC) selected from:

* Note: Students may take either ANAT 321 OR ANAT 323.

  • ANAT 314 Human Musculoskeletal Anatomy (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Introduction to the gross anatomy of the musculoskeletal system (bone, joints, muscles and neurovascular structures) of the head, neck, trunk, upper and lower limb regions of the human body, emphasizing functional anatomy and including surface anatomy and imaging. Exploration of the human body through cadaveric prosections, imaging and other materials.

    Terms: Winter 2025

    Instructors: Rolian, Campbell (Winter)

    • Winter

    • Prerequisite: ANAT 214

    • Restrictions: Not open to students who have taken or are taking ANAT 315.

    • 2 hours lectures, 2 hours laboratory

  • ANAT 321 Circuitry of the Human Brain (3 credits) **

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.

    Terms: Fall 2024

    Instructors: Ragsdale, David S (Fall)

  • ANAT 322 Neuroendocrinology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.

    Terms: Winter 2025

    Instructors: Walker, Claire; Stroh, Thomas; Tamilia, Michael; Cermakian, Nicolas; Bernard, Daniel; Kokoeva, Maia; Storch, Kai-Florian (Winter)

    • Winter

    • 3 hours lecture

    • Prerequisite: PHGY 210.

  • ANAT 323 Clinical Neuroanatomy (3 credits) **

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course will focus on the structural and functional relationships of the central nervous system. The human neuroanatomy will be introduced via pathological cases and will be illustrated by use of new medical imaging techniques.

    Terms: Fall 2024

    Instructors: Stiver, Mikaela (Fall)

    • Prerequisites for Physical & Occupational Therapy students: ANAT 315 and ANAT 316

    • Prerequisites for Honours Anatomy & Cell Biology students: ANAT 214 and ANAT 314.

    • Restrictions: Restricted to Honours Anatomy & Cell Biology students and Physical & Occupational Therapy students.

    • Not open to students who have taken or are taking ANAT 321.

  • ANAT 365 Cellular Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.

    Terms: Fall 2024

    Instructors: Zeytuni, Natalie; McBride, Heidi; Kennedy, Timothy E; Stroh, Thomas; Presley, John; Sossin, Wayne Steven; Estall, Jennifer (Fall)

  • ANAT 381 Experimental Embryology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : The basic processes of reproduction and embryonic development, such as molecular signaling; cell-cell interaction; differentiation; cell fate determination; genetic and epigenetic control of embryonic development.

    Terms: Fall 2024

    Instructors: Nagano, Makoto; Ao, Asangla; Ryan, Aimee; Clarke, Hugh; Tanny, Jason (Fall)

    • Fall

    • 3 hour lectures

    • Prerequisites: ANAT 261, BIOL 202 or permission of instructor

    • Restriction(s): Not open to students who have taken BIOL 303.

  • ANAT 416 Development, Disease and Regeneration (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Importance of developmental biology for disease and regeneration. Topics: advanced developmental biology principles; molecular basis for stem cells and their potential applications; organogenesis and its applications to various diseases.

    Terms: Winter 2025

    Instructors: Bui, Khanh Huy; Chang, Natasha; Charron, Frederic; Bateman, Andrew; Liu, Jun-Li; Siegel, Peter; Cayouette, Michel; Rocheleau, Christian; Andelfinger, Gregor; McCaffrey, Luke (Winter)

    • Winter

    • 3 hours lecture

    • Prerequisite(s): ANAT 381 or BIOL 303 or special permission of instructor

  • ANAT 458 Membranes and Cellular Signaling (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2025

    Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter; Zeytuni, Natalie (Winter)

  • ANAT 514 Advanced Human Anatomy Laboratory (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : A laboratory course exploring human anatomy education through regionally focused dissection-based projects and applications of technology in anatomy teaching and learning.

    Terms: Winter 2025

    Instructors: Venne, Gabriel (Winter)

    • Prerequisites: ANAT 214 and ANAT 314

    • Restrictions: Open to U3 Anatomy & Cell Biology students

    • 1 hour lecture, 4 hours laboratory

  • ANAT 541 Cell and Molecular Biology of Aging (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Complex aging process, including theories and mechanisms of aging, animal model systems used to study aging, age-dependent diseases, for example, Alzheimer's, osteoporosis, and cancer, and age-related diseases, for example, Werner's syndrome and dyskeratosis congenita.

    Terms: Winter 2025

    Instructors: Autexier, Chantal; Mercier, Francois; Siegel, Peter; Lehoux, Stephanie; Haglund, Lisbet; Crist, Colin; Gerhold, Abigail; Vera Ugalde, Maria (Winter)

  • ANAT 542 Transmission Electron Microscopy of Biological Samples (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Overview of theory, principles and practical applications of conventional and cryo-transmission electron microscopy relevant to biological samples. Major topics to be covered include: sample preparation and imaging, image analysis, three-dimensional reconstruction (including single-particle analysis an tomography).

    Terms: Winter 2025

    Instructors: Zeytuni, Natalie; McKee, Marc D; Bui, Khanh Huy; Reznikov, Natalie; Guo, Shuaiqi (Winter)

    • Prerequisite(s): Permission of instructor

    • 2 hours lectures, 3 hours laboratory

  • ANAT 565 Diseases-Membrane Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course will examine how research into diseases has played a key role in unraveling the intricate molecular mechanisms controlling membrane trafficking in mammalian cells. Membrane trafficking disorders fall into two groups those arising from a) membrane-associated or b) cytoskeletal defect. Topics include a) mechanisms of endosomal maturation, lysosomal storage disorders and rab protein-mediated vesicular trafficking and b) rho GTPase and cytoskeletal binding protein mediated trafficking associated with neurological diseases and cancer.

    Terms: Winter 2025

    Instructors: Presley, John; Lefrancois, Stephane; Lamarche, Nathalie; Nilsson, Tommy; Pshezhetsky, Alexei (Winter)

  • NEUR 310 Cellular Neurobiology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Science)

    Overview

    Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.

    Terms: Winter 2025

    Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E; Fournier, Alyson Elise; Sossin, Wayne Steven; Ruthazer, Edward; Fortin, Jerome (Winter)

3 credits of biologically oriented courses (BOC) selected from:

  • ANAT 314 Human Musculoskeletal Anatomy (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Introduction to the gross anatomy of the musculoskeletal system (bone, joints, muscles and neurovascular structures) of the head, neck, trunk, upper and lower limb regions of the human body, emphasizing functional anatomy and including surface anatomy and imaging. Exploration of the human body through cadaveric prosections, imaging and other materials.

    Terms: Winter 2025

    Instructors: Rolian, Campbell (Winter)

    • Winter

    • Prerequisite: ANAT 214

    • Restrictions: Not open to students who have taken or are taking ANAT 315.

    • 2 hours lectures, 2 hours laboratory

  • ANAT 321 Circuitry of the Human Brain (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.

    Terms: Fall 2024

    Instructors: Ragsdale, David S (Fall)

  • ANAT 322 Neuroendocrinology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.

    Terms: Winter 2025

    Instructors: Walker, Claire; Stroh, Thomas; Tamilia, Michael; Cermakian, Nicolas; Bernard, Daniel; Kokoeva, Maia; Storch, Kai-Florian (Winter)

    • Winter

    • 3 hours lecture

    • Prerequisite: PHGY 210.

  • ANAT 323 Clinical Neuroanatomy (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course will focus on the structural and functional relationships of the central nervous system. The human neuroanatomy will be introduced via pathological cases and will be illustrated by use of new medical imaging techniques.

    Terms: Fall 2024

    Instructors: Stiver, Mikaela (Fall)

    • Prerequisites for Physical & Occupational Therapy students: ANAT 315 and ANAT 316

    • Prerequisites for Honours Anatomy & Cell Biology students: ANAT 214 and ANAT 314.

    • Restrictions: Restricted to Honours Anatomy & Cell Biology students and Physical & Occupational Therapy students.

    • Not open to students who have taken or are taking ANAT 321.

  • ANAT 365 Cellular Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.

    Terms: Fall 2024

    Instructors: Zeytuni, Natalie; McBride, Heidi; Kennedy, Timothy E; Stroh, Thomas; Presley, John; Sossin, Wayne Steven; Estall, Jennifer (Fall)

  • ANAT 381 Experimental Embryology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : The basic processes of reproduction and embryonic development, such as molecular signaling; cell-cell interaction; differentiation; cell fate determination; genetic and epigenetic control of embryonic development.

    Terms: Fall 2024

    Instructors: Nagano, Makoto; Ao, Asangla; Ryan, Aimee; Clarke, Hugh; Tanny, Jason (Fall)

    • Fall

    • 3 hour lectures

    • Prerequisites: ANAT 261, BIOL 202 or permission of instructor

    • Restriction(s): Not open to students who have taken BIOL 303.

  • ANAT 416 Development, Disease and Regeneration (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Importance of developmental biology for disease and regeneration. Topics: advanced developmental biology principles; molecular basis for stem cells and their potential applications; organogenesis and its applications to various diseases.

    Terms: Winter 2025

    Instructors: Bui, Khanh Huy; Chang, Natasha; Charron, Frederic; Bateman, Andrew; Liu, Jun-Li; Siegel, Peter; Cayouette, Michel; Rocheleau, Christian; Andelfinger, Gregor; McCaffrey, Luke (Winter)

    • Winter

    • 3 hours lecture

    • Prerequisite(s): ANAT 381 or BIOL 303 or special permission of instructor

  • ANAT 458 Membranes and Cellular Signaling (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2025

    Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter; Zeytuni, Natalie (Winter)

  • ANAT 541 Cell and Molecular Biology of Aging (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Complex aging process, including theories and mechanisms of aging, animal model systems used to study aging, age-dependent diseases, for example, Alzheimer's, osteoporosis, and cancer, and age-related diseases, for example, Werner's syndrome and dyskeratosis congenita.

    Terms: Winter 2025

    Instructors: Autexier, Chantal; Mercier, Francois; Siegel, Peter; Lehoux, Stephanie; Haglund, Lisbet; Crist, Colin; Gerhold, Abigail; Vera Ugalde, Maria (Winter)

  • ANAT 542 Transmission Electron Microscopy of Biological Samples (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : Overview of theory, principles and practical applications of conventional and cryo-transmission electron microscopy relevant to biological samples. Major topics to be covered include: sample preparation and imaging, image analysis, three-dimensional reconstruction (including single-particle analysis an tomography).

    Terms: Winter 2025

    Instructors: Zeytuni, Natalie; McKee, Marc D; Bui, Khanh Huy; Reznikov, Natalie; Guo, Shuaiqi (Winter)

    • Prerequisite(s): Permission of instructor

    • 2 hours lectures, 3 hours laboratory

  • ANAT 565 Diseases-Membrane Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course will examine how research into diseases has played a key role in unraveling the intricate molecular mechanisms controlling membrane trafficking in mammalian cells. Membrane trafficking disorders fall into two groups those arising from a) membrane-associated or b) cytoskeletal defect. Topics include a) mechanisms of endosomal maturation, lysosomal storage disorders and rab protein-mediated vesicular trafficking and b) rho GTPase and cytoskeletal binding protein mediated trafficking associated with neurological diseases and cancer.

    Terms: Winter 2025

    Instructors: Presley, John; Lefrancois, Stephane; Lamarche, Nathalie; Nilsson, Tommy; Pshezhetsky, Alexei (Winter)

  • BIOC 311 Metabolic Biochemistry (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.

    Terms: Fall 2024

    Instructors: Denis, Maxime; Giguere, Vincent; Gehring, Kalle; Kazak, Lawrence (Fall)

  • BIOC 312 Biochemistry of Macromolecules (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).

    Terms: Winter 2025

    Instructors: Huang, Sidong; Sonenberg, Nahum; Tremblay, Michel; Dostie, Josee; Giguere, Vincent; Vera Ugalde, Maria (Winter)

  • BIOC 450 Protein Structure and Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.

    Terms: Fall 2024

    Instructors: Nagar, Bhushan; Schmeing, Martin; Purisima, Enrico; Gehring, Kalle; von Roretz, Christopher; Thibodeaux, Christopher; Guarne, Alba; Vera Ugalde, Maria; Zeytuni, Natalie (Fall)

    • Fall

    • Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry.

    • Restriction: Intended primarily for students at the U3 level

  • BIOC 458 Membranes and Cellular Signaling (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2025

    Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)

  • BIOC 503 Biochemistry of Immune Diseases (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Current selected topics in immunology. The biochemical mechanisms underlying various immuno-pathologies and the clinical significance of therapeutic interventions.

    Terms: Winter 2025

    Instructors: Tsoukas, Christos M; Denis, Maxime (Winter)

  • BIOL 300 Molecular Biology of the Gene (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.

    Terms: Fall 2024

    Instructors: Sch枚ck, Frieder; Moon, Nam Sung (Fall)

  • BIOL 303 Developmental Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.

    Terms: Winter 2025

    Instructors: Gerhold, Abigail; Rao, Yong; Dufort, Daniel (Winter)

  • BIOL 306 Neural Basis of Behaviour (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.

    Terms: Fall 2024

    Instructors: Sakata, Jon; Dent, Joseph Alan; Oyama, Tomoko (Fall)

  • BIOL 313 Eukaryotic Cell Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : In-depth examination of the structure and function of eukaryotic cells, with an emphasis on experimental design and interpretation. Examination of the molecular mechanisms of various cellular processes, including protein homeostasis, intracellular transport, cytoskeletal dynamics, multicellular organization and cell proliferation.

    Terms: Winter 2025

    Instructors: Weber, Stephanie (Winter)

  • BIOL 314 Molecular Biology of Cancer (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The molecular basis of human cancers, including analyzing the events that promote the formation of oncogenes and inhibit tumour suppressor genes, the biochemical properties of the proteins encoded by these genes, and their functions. Current molecular targets for cancer therapy and the concepts and consequences of inheriting mutations in genes that predispose to cancer.

    Terms: Winter 2025

    Instructors: Dankort, David (Winter)

  • BIOL 320 Evolution of Brain and Behaviour (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Functional and comparative approach to neuroanatomy, examining how species changes in brain organization contribute to evolutionary changes in behaviour.

    Terms: Winter 2025

    Instructors: Woolley, Sarah; Sakata, Jon (Winter)

    • Winter

    • 2 hours of lecture and 1 hour of conference (mandatory)

    • Prerequisite: NSCI 201 or BIOL 306

  • BIOL 370 Human Genetics Applied (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A contemporary view of genetic research as applied to human health and well-being.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

  • BIOL 518 Advanced Topics in Cell Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Concepts and mechanisms in advanced cell biology, based on genetic, cell biological, biophysical, and computational studies. Emphasis is placed on processes that are evolutionarily conserved, with examples from model organisms and cell-free (in vitro) approaches.

    Terms: Winter 2025

    Instructors: Harrison, Paul; Lasko, Paul; Brouhard, Gary (Winter)

    • Winter

    • 3 hours seminar

    • Prerequisite: BIOL 313 or permission

  • BIOL 520 Gene Activity in Development (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : An analysis of the role and regulation of gene expression in several models of eukaryotic development. The emphasis will be on critical evaluation of recent literature concerned with molecular or genetic approaches to the problems of cellular differentiation and determination. Recent research reports will be discussed in conferences and analyzed in written critiques.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

    • Winter

    • 3 hours lecture and discussion

    • Prerequisites: BIOL 300 and BIOL 303 or permission

  • BIOL 524 Topics in Molecular Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Molecular genetics and molecular, cellular and developmental biology, including signal transduction, cell differentiation and function, genetic diseases in eukaryotes.

    Terms: Fall 2024

    Instructors: Clarke, Hugh; Dankort, David (Fall)

  • BIOL 532 Developmental Neurobiology Seminar (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Discussions of all aspects of nervous system development including pattern formation, cell lineage, pathfinding and targeting by growing axons, and neural regeneration. The basis for these discussions will be recent research papers and other assigned readings.

    Terms: Winter 2025

    Instructors: Van Meyel, Donald; Kania, Artur; Fournier, Alyson Elise; Cloutier, Jean-Francois; Ruthazer, Edward (Winter)

    • Winter

    • 1 hour lecture, 2 hours seminar

    • Prerequisites: BIOL 303 or BIOL 306 or permission of instructor

  • BIOL 544 Genetic Basis of Life Span (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The course will consider how gene action is determining the duration of life in various organisms focusing on the strengths and limitations of the genetic approach. The course will focus particularly on model organisms such as yeast, Caenorhabditis, Drosophila and mouse, as well as on the characterization of long-lived people.

    Terms: Fall 2024

    Instructors: Hekimi, Siegfried (Fall)

  • BIOL 546 Genetics of Model Systems (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Topics in the genetics and molecular genetics of unicellular, plant, invertebrate and vertebrate models systems.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

  • BIOL 551 Principles of Cellular Control (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Fundamental principles of cellular control, with cell cycle control as a major theme. Biological and physical concepts are brought to bear on control in healthy cells..

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

  • BIOL 575 Human Biochemical Genetics (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Selected human diseases, from the molecular and cellular levels to tissue effects and emerging novel therapies.

    Terms: Fall 2024

    Instructors: Braverman, Nancy; Genest, Jacques Jean; Paliouras, Miltiadis; Christensen, Karen Elizabeth; Rauch, Frank; Watkins, David; Shoubridge, Eric Alan; Pshezhetsky, Alexei; Kitzler, Thomas; Armstrong, Gary (Fall)

  • BIOL 588 Advances in Molecular/Cellular Neurobiology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Discussion of fundamental molecular mechanisms underlying the general features of cellular neurobiology. An advanced course based on lectures and on a critical review of primary research papers.

    Terms: Fall 2024

    Instructors: Hastings, Kenneth E M; Nagy, Corina; McPherson, Peter Scott; Poulin, Jean-Francois; Zhou, Yang (Fall)

    • Fall

    • 1.5 hours lecture, 1.5 hours seminar

    • Prerequisite: BIOL 300 and BIOL 306 or permission

  • BIOT 505 Selected Topics in Biotechnology (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.

    Terms: Fall 2024

    Instructors: Harpp, David Noble; Schwarcz, Joseph A (Fall)

    • Fall

    • Restriction: U3 students

  • COMP 204 Computer Programming for Life Sciences (3 credits)

    Offered by: Computer Science (Faculty of Science)

    Overview

    Computer Science (Sci) : Computer Science (Sci): Computer programming in a high level language: variables, expressions, types, functions, conditionals, loops, objects and classes. Introduction to algorithms, modular software design, libraries, file input/output, debugging. Emphasis on applications in the life sciences.

    Terms: Fall 2024, Winter 2025

    Instructors: Becerra, David (Fall) Siddiqi, Kaleem (Winter)

    • Co-requisite: BIOL 112

    • Restrictions: Not open to students who have taken or are taking COMP 202, COMP 208, or GEOG 333; not open to students who have taken or are taking COMP 206 or COMP 250.

    • To take COMP 204, students should have a solid understanding of pre-calculus fundamentals such as polynomial, trigonometric, exponential, and logarithmic functions.

  • EXMD 401 Physiology and Biochemistry Endocrine Systems (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.

    Terms: Winter 2025

    Instructors: Liu, Jun-Li; Bateman, Andrew; O'Flaherty, Cristian; Bernard, Daniel; Murshed, Monzur; Sabatini, Paul (Winter)

  • EXMD 502 Advanced Endocrinology 1 (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : This course is designed for U3 students who are in a major or honours program in anatomy, biology, biochemistry or physiology and for graduate students. A multidisciplinary approach will be used to teach biosynthesis and processing of hormones, their regulation, function and mechanism of action. The material will cover hypothalamic, pituitary, thyroid, atrial and adrenal hormones as well as prostaglandins and related substances.

    Terms: Fall 2024

    Instructors: Kokoeva, Maia; Stroh, Thomas; Bateman, Andrew; Ali, Suhad; Morris, David; Giguere, Vincent; Laporte, Stephane; Rocheleau, Christian; Kiss, Robert; Murshed, Monzur (Fall)

    • Fall

  • EXMD 503 Advanced Endocrinology 02 (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Study of the parathyroids, gut and pancreatic hormones and growth factors. In addition, the role of hormones and growth factors in reproduction and fetal maturation will be discussed.

    Terms: Winter 2025

    Instructors: Bateman, Andrew; Kokoeva, Maia (Winter)

    • Winter

  • EXMD 504 Biology of Cancer (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.

    Terms: Fall 2024

    Instructors: Garzia, Livia; Teodoro, Jose Guerreiro; Gold, Phil; Brodt, Penina; Tonin, Patricia; Bailey, Swneke; Fortin, Jerome; Malag贸n, Tal铆a; Jung, Sungmi; Labb茅, David (Fall)

    • Fall

    • Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only

  • EXMD 506 Advanced Applied Cardiovascular Physiology (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. Current topics, methods and techniques for studying the cardiovascular system. Basic and applied cardiac electrophysiology, mechanisms of pacemaker activity, arrhythmias, the effects of drugs on cardiac functions, fetal circulation, coronary circulation, mechanics of blood flow, cardiovascular diseases, renal and neural control of the circulation, and cardiac assist devices.

    Terms: Fall 2024

    Instructors: Schwertani, Adel; Bottega, Natalie Ann; Dandona, Kshitij Badal; Bernier, Martin Louis; Genest, Jacques Jean; Shum-Tim, Dominique; Guevara, Michael R; de Varennes, Benoit; Friedrich, Matthias Gero (Fall)

  • EXMD 507 Advanced Applied Respiratory Physiology (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. In depth coverage of respiratory biology including: functional anatomy of the respiratory system, pulmonary statics and dynamics, chest wall and respiratory muscles, ventilation and perfusion, control of breathing, and defense mechanisms. This course is aimed at providing a solid grounding in pulmonary biology and its research applications.

    Terms: Fall 2024

    Instructors: Petrof, Basil; Azuelos, Ilan; Kristof, Arnold Scott; Kaminska, Marta; Smith, Benjamin; Martin, James G; Eidelman, David H; Lauzon, Anne-Marie; Hussain, Sabah N A; Kimoff, John R (Fall)

  • EXMD 508 Advanced Topics in Respiration (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. In depth coverage of developmental physiology, pulmonary vascular physiology, biology of airway smooth muscle, respiratory epithelium and molecular biology of respiratory muscles. Dyspnea, mechanical ventilation and respiratory failure will also be covered. This course emphasizes application of respiratory biology to basic and applied research and touches on pulmonary pathophysiology.

    Terms: Winter 2025

    Instructors: Fixman, Elizabeth Dee (Winter)

  • MIMM 314 Intermediate Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An intermediate-level immunology course covering the cellular and molecular basis of lymphocyte development and activation in immune responses in health and disease.

    Terms: Winter 2025

    Instructors: Piccirillo, Ciriaco; King, Irah; Melichar, Heather (Winter)

    • Winter

    • 3 hours of lecture

    • Prerequisite: MIMM 214

  • MIMM 323 Microbial Physiology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An introduction to the composition and structure of microbial cells, the biochemical activities associated with cellular metabolism and how these activities are regulated and coordinated. The course will have a molecular and genetic approach to the study of microbial physiology.

    Terms: Fall 2024

    Instructors: Marczynski, Gregory T (Fall)

    • Fall

    • 3 hours of lecture

    • Prerequisite: MIMM 211

  • MIMM 324 Fundamental Virology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : A study of the fundamental properties of viruses and their interactions with host cells. Bacteriophages, DNA- and RNA-containing animal viruses, and retroviruses are covered. Emphasis will be on phenomena occurring at the molecular level and on the regulated control of gene expression in virus-infected cells.

    Terms: Fall 2024

    Instructors: Teodoro, Jose Guerreiro; Liang, Chen; Kukolj, George; Briedis, Dalius J; Mouland, Andrew J; Archambault, Jacques; Liu, Qian; Liu, Leo (Fall)

  • MIMM 387 The Business of Science (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has led to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.

    Terms: Winter 2025

    Instructors: Kukolj, George (Winter)

    • Winter

    • Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor

  • MIMM 413 Parasitology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : A study of the biology, immunological aspects of host-parasite interactions, pathogenicity, epidemiology and molecular biological aspects of selected parasites of medical importance. Laboratory will consist of a lecture on techniques, demonstrations and practical work.

    Terms: Winter 2025

    Instructors: Matlashewski, Greg J; Ndao, Momar (Winter)

    • Winter

    • Prerequisite: MIMM 314 or equivalent - ANAT 261 is strongly recommended

  • MIMM 414 Advanced Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.

    Terms: Fall 2024

    Instructors: Fritz, J枚rg (Fall)

    • Fall

    • 3 hour lecture

    • Prerequisite: MIMM 314

  • MIMM 465 Bacterial Pathogenesis (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : Familiarizes students with key principles and recent advances in our understanding of the strategies that bacteria use to infect and cause disease, as well as the approaches used in the prevention and treatment of bacterial infections.

    Terms: Fall 2024

    Instructors: Reed, Michael; Nguyen, Dao; Behr, Marcel A; Denis, Maxime; Gruenheid, Samantha; Veyrier, Fr茅d茅ric; Ronholm, Jennifer; Maurice, Corinne; Lupien, Andr茅anne (Fall)

  • MIMM 466 Viral Pathogenesis (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection.

    Terms: Winter 2025

    Instructors: Liang, Chen (Winter)

  • MIMM 509 Inflammatory Processes (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from 不良研究所 and other universities) and students will be furthered.

    Terms: Winter 2025

    Instructors: Rauch, Joyce; Di Battista, Giovanni (John) (Winter)

    • Winter

    • 3 hours of seminar

    • Corequisite: PHGY 513 or MIMM 414

    • This course will be given in conjunction with the Division of Experimental Medicine

    • Prerequisite: MIMM 314

  • NEUR 310 Cellular Neurobiology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Science)

    Overview

    Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.

    Terms: Winter 2025

    Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E; Fournier, Alyson Elise; Sossin, Wayne Steven; Ruthazer, Edward; Fortin, Jerome (Winter)

  • NEUR 502 Basic and Clinical Aspects of Neuroimmunology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Medicine and Health Sciences)

    Overview

    Neurology and Neurosurgery : The role of inflammation in physiological function of the nervous system, as well as in a broad range of neurological diseases where inflammation can act as a contributing factor to the development of pathology or promote recovery, including fundamentals of neuroimmunology to molecular/cellular aspects of neuroinflammation underlying the pathology seen in clinical conditions.

    Terms: Winter 2025

    Instructors: Zhang, Ji; Antel, Jack P; Cermakian, Nicolas; Stratton, Jo Anne (Winter)

  • PATH 300 Human Disease (3 credits)

    Offered by: Pathology (Faculty of Science)

    Overview

    Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.

    Terms: Winter 2025

    Instructors: Zorychta, Edith (Winter)

  • PHAR 300 Drug Action (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.

    Terms: Fall 2024

    Instructors: Zorychta, Edith; Thanabalasuriar, Ajitha; Bernard, Daniel (Fall)

  • PHAR 301 Drugs and Disease (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.

    Terms: Winter 2025

    Instructors: Castagner, Bastien; Robaire, Bernard; Clarke, Paul; Bowie, Derek; Thanabalasuriar, Ajitha (Winter)

  • PHAR 303 Principles of Toxicology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.

    Terms: Winter 2025

    Instructors: McKeague, Maureen; Zorychta, Edith; Robaire, Bernard; Baglole, Carolyn (Winter)

  • PHAR 562 Neuropharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system.

    Terms: Fall 2024

    Instructors: Bowie, Derek; Trempe, Jean-Francois; Leyton, Marco; McKinney, R. Anne; Stellwagen, David; Khoutorsky, Arkady; Multhaup, Gerhard; Munter, Lisa (Fall)

    • Fall

    • Prerequisite: PHAR 301 or with permission of instructor.

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

  • PHAR 563 Endocrine Pharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This advanced course covers selected topics in pharmacology of reproductive, endocrine, and metabolic disorders.

    Terms: Fall 2024

    Instructors: Bernard, Daniel; Robaire, Bernard; Trasler, Jacquetta M (Fall)

    • Prerequisite: PHAR 301 or permission of the instructor(s)

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

    • Course material will be presented in the form of lectures and student-led presentations.

  • PHGY 311 Channels, Synapses and Hormones (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.

    Terms: Fall 2024

    Instructors: Cooper, Ellis; Sj枚str枚m, Jesper; Krishnaswamy, Arjun; Sharif Naeini, Reza (Fall)

    • Fall

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term

    • Prerequisite: PHGY 209 or permission of the instructor.

  • PHGY 312 Respiratory, Renal, and Cardiovascular Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.

    Terms: Winter 2025

    Instructors: Hanrahan, John W; Martin, James G; Shrier, Alvin; Magder, Sheldon A (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 313 Blood, Gastrointestinal, and Immune Systems Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.

    Terms: Winter 2025

    Instructors: Mandl, Judith; Blank, Volker Manfred; Vollrath, Melissa; Fritz, J枚rg; Quail, Daniela (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 314 Integrative Neuroscience (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.

    Terms: Fall 2024

    Instructors: Chacron, Maurice; Pack, Christopher; Shmuel, Amir; Vollrath, Melissa; Lomber, Stephen; Brandon, Mark; Bashivan, Pouya (Fall)

    • Fall

    • 3 hours of lectures per week

    • Prerequisites: PHGY 209

  • PHGY 451 Advanced Neurophysiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Topics of current interest in neurophysiology including the development of neurons and synapses, physiology of ionic channels, presynaptic and postsynaptic events in synaptic transmission and neuronal interactions in CNS function.

    Terms: Fall 2024

    Instructors: Cooper, Ellis; Krishnaswamy, Arjun; Bourque, Charles W; Chacron, Maurice; Suvrathan, Aparna (Fall)

    • Fall

    • 3 hours lecture

    • Prerequisite: PHGY 311 or equivalent

    • Restriction: Departmental approval required

  • PHGY 502 Exercise Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Behaviour of physiological processes in response to physical effort, in areas such as structural basis of muscle contraction, thermoregulation during exercise, mechanics and energetics of muscle contraction, fuel utilization, fatigue, physiological adjustments during exercise and influence of training.

    Terms: Winter 2025

    Instructors: Rousseau, Simon; Comtois, Alain Steve; Martin, James G; Magder, Sheldon A; Hussain, Sabah N A; Lands, Larry; Petrof, Basil (Winter)

  • PHGY 508 Advanced Renal Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Advanced concepts in selected areas of kidney physiology, including the glomerulus, renal cell biology, kidney development, membrane and epithelial transport, hormones and autacoids, kidney transplantation, bioengineering and regenerative medicine.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

    • Fall. Offered in conjunction with the Department of Medicine.

    • Prerequisite (Undergraduate): PHGY 312 or the equivalent

    • Restriction: Open to advanced undergraduate and graduate students

  • PHGY 513 Translational Immunology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Advanced key concepts in immunology as they relate to health and disease, including infectious diseases, non-infectious diseases and autoimmunity, and cancer immunology.

    Terms: Winter 2025

    Instructors: Quail, Daniela; Behr, Marcel A; Rauch, Joyce; Antel, Jack P; Bernard, Nicole F; Schurr, Erwin; Ward, Brian; Fritz, J枚rg; Nijnik, Anastasia; Mandl, Judith (Winter)

    • Winter

    • 3 hours lectures

    • Prerequisite: MIMM 314 or PHGY 313 or permission of the instructor

  • PHGY 515 Blood-Brain Barrier in Health and Disease (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Molecular and cellular mechanisms underlying the organization and regulation of the blood-brain barrier, highlighting neurological diseases associated with the blood-brain barrier breakdown and give an overview of experimental approaches to study blood-brain barrier.

    Terms: Fall 2024

    Instructors: Prager-Khoutorsky, Maria; Zhang, Ji; Kostikov, Alexey; Munter, Lisa; Rudko, David; Diaz, Roberto; Stratton, Jo Anne (Fall)

    • Fall

    • 1.5 hours Lecture and 1.5 hours Seminar weekly

    • Prerequisite: PHGY 313 or PHGY 314 and permission of the instructor

  • PHGY 516 Physiology of Blood (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Bone marrow hematopoiesis, with emphasis on regulation of stem cell proliferation and differentiation along hematopoietic pathways. Formation and differentiation of red and white blood cells and some of the diseases associated with hematopoiesis will be covered. Emphasis will be given to the molecular mechanisms involved in the normal and pathological conditions.

    Terms: Winter 2025

    Instructors: Blank, Volker Manfred; Pantopoulos, Konstantinos; Nijnik, Anastasia (Winter)

    • Winter

    • 2 hours lecture plus 1 hour seminar weekly

  • PHGY 518 Artificial Cells (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology, biotechnology, chemistry and biomedical application of artificial cells, blood substitutes, immobilized enzymes, microorganisms and cells, hemoperfusion, artificial kidneys, and drug delivery systems. PHGY 517 and PHGY 518 when taken together, will give a complete picture of this field. However, the student can select one of these.

    Terms: Fall 2024

    Instructors: Chang, Thomas Ming Swi; Shum-Tim, Dominique; Prakash, Satya; Hoesli, Corinne; Chen, Guojun (Fall)

    • Fall

    • Prerequisite (Undergraduate): permission of instructors.

  • PHGY 552 Cellular and Molecular Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.

    Terms: Winter 2025

    Instructors: Orlowski, John; White, John H; Stochaj, Ursula; Bernard, Daniel (Winter)

    • Winter

    • 1 hour lecture, 2 hours seminar weekly

    • Prerequisite: PHGY 311

    • Preference will be given to Physiology Honours and Graduate students

  • PHGY 556 Topics in Systems Neuroscience (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Topics of current interest in systems neurophysiology and behavioural neuroscience including: the neural representation of sensory information and motor behaviours, models of sensory motor integration, and the computational analysis of problems in motor control and perception. Students will be expected to present and critically discuss journal articles in class.

    Terms: Winter 2025

    Instructors: Guitton, Daniel E; Baker, Curtis L; Cook, Erik; Pack, Christopher; Peyrache, Adrien; Krishna, Suresh; Bashivan, Pouya; Mohajerani, Majid (Winter)

    • Winter

    • Restriction: Permission of the instructor required.

    • Restriction: Not open to students who have taken PHGY 456

  • PSYT 455 Neurochemistry (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.

    Terms: This course is not scheduled for the 2024-2025 academic year.

    Instructors: There are no professors associated with this course for the 2024-2025 academic year.

  • PSYT 500 Advances: Neurobiology of Mental Disorders (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Current theories on the neurobiological basis of most well known mental disorders (e.g. schizophrenia, depression, anxiety, dementia). Methods and strategies in research on genetic, physiological and biochemical factors in mental illness will be discussed. Discussion will also focus on the rationale for present treatment approaches and on promising new approaches.

    Terms: Winter 2025

    Instructors: Wong, Tak Pan; Nagy, Corina; Chakravarty, Megha; Tritsch, Nicolas; Beaulieu, Serge; Gobbi, Gabriella; Poirier, Judes; Srivastava, Lalit K; Leyton, Marco; Silveira, Patricia (Winter)

    • Winter

    • 3 hours

    • Prerequisite (Undergraduate): BIOC 212 and BIOC 311, or BIOC 312, or BIOL 200 and BIOL 201, or PHGY 311, or PSYC 308 and an upper-level biological science course with permission of the instructors, or equivalent. Basic knowledge of cellular and molecular biology is required.

    • Restriction: Open to U3 and graduate students only.

    • Restriction: Graduate Studies: strongly recommended for M.Sc. students in Psychiatry.

Faculty of Science—2024-2025 (last updated Aug. 21, 2024) (disclaimer)
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