Lisbet Haglund
Professor
PhD
Basic spinal research focusing on:
- Evaluating the potential for disc repair in early to moderate stages of disc degeneration. The overall goal is to show that it is possible to restore the integrity of the degenerated disc matrix with biological means.
- To identify novel markers of early disc degeneration (other than those generated in the intervertebral disc as a consequence of ageing).
- Characterization of changes in protein composition of the extra cellular matrix from scoliotic discs compared to normal control discs. This study will increase the understanding of composition and function of the extracellular matrix and provide a link between biochemical composition and biomechanical properties in normal and pathophysiological conditions.
The projects utilize a variety of techniques in protein biochemistry, and cell biology.
Lisbet Haglund is a basic scientist and a tenured Professor in the Department of Surgery, Division of Orthopaedic Surgery at 不良研究所, Montreal, Quebec, Canada. Professor Haglund has a strong interest in musculoskeletal research spanning from tissue injury, degeneration, and inflammation to regenerative medicine, and she has been actively involved in bone, cartilage, and intervertebral disc research throughout her career. She has developed a research program aiming to enhance our understanding of the molecular mechanisms leading to pain in spine pathology. More precisely, to develop molecular markers to follow disease state, progression, or effect of treatment, and most importantly to develop novel therapeutic interventions for painful spine conditions. Professor Haglund is a member of the 不良研究所 Scoliosis and Spine Group, and she is working closely with the clinical team. This has allowed her to generate an extensive cell and tissue bank of symptomatic (surgical) and non-symptomatic (organ donor) cells and tissues. Her research program is currently funded through the Canadian Institute for Health Research (CIHR), the Shriners Hospital for Children and the Arthritis Society.
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