Broadly speaking, research at the CRN has the following major goals: 1) to understand the cellular and molecular mechanisms of central nervous system (CNS) function,听2) to determine how the CNS is assembled during development and 3) to discover how it can be remodeled in response to injuries or disease. Here is a brief overview, but click here for more in-depth descriptions听of the research being done in听each CRN Research Lab.
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- Growth and guidance of axons and dendrites
- Synapse formation
- Neuron-glial interactions
- Neurodegeneration and regeneration
- Synaptic plasticity and homeostasis
- Neural circuit assembly and function
- Behavior
- Advanced cellular and molecular approaches
- Classical and next-generation genetics
- Hi-resolution confocal and multi-photon听imaging
- Opto-genetics
- Sophisticated electrophysiology
- Traumatic injuries to the brain or spinal cord
- Autism spectrum disorders
- Mental retardation
- Multiple sclerosis
- Epilepsy
- Stroke
- Addiction
- Alzheimer's, Parkinson鈥檚 and Huntington鈥檚 diseases
- Episodic ataxia
- Hemiplegic migraine
- Schizophrenia
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